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Feasibility and Acceptability of Instructions of Daily Care in Overweight and Obese Knee Osteoarthritis Participants


Muhammad Tariq Rafiq*, Mohamad Shariff A Hamid, Eliza Hafiz, Farid Ahmad Chaudhary and Muhammad Irfan Khan   Pages 1 - 7 ( 7 )


Introduction: Knee Osteoarthritis (OA) is a weight-bearing joint disease and is more common in overweight and obese persons. The objective of the study was to assess the feasibility and acceptability of Instructions of Daily Care (IDC) on pain, mobility, and Body Mass Index (BMI) among knee OA participants who are overweight or obese.

Materials and Methods: The study was an open-label randomized controlled trial of six weeks. Forty overweight and obese participants with knee OA were randomly divided into two groups by a computer-generated number. The participants in the Instruction Group (IG) were provided with leaflets explaining IDC for the duration of six weeks. Both groups were instructed to take low doses of the non-steroid anti-inflammatory drug (NSAIDs) on alternate days. The outcome measures were pain, mobility and BMI. The feasibility and acceptability of knee pain and mobility were assessed using a questionnaire designed by experts in rehabilitation.

Results: Participants in the IG reported more statistically significant pain relief as assessed by the Western Ontario and McMaster Universities Osteoarthritis Index score (p=0.001) and improvement in mobility (p=0.000) assessed by the Timed Up and Go test score after six weeks compared to the Control Group (CG). Both groups did not demonstrate any significant change in BMI (p-value > 0.05). The results of descriptive statistics showed a significantly higher satisfaction score for participants who received a combination of IDC and NSAIDs, indicating an acceptable intervention.

Conclusion: The IDC is effective and acceptable in terms of improving pain and mobility and should be recommended as the usual care of treatment.

Clinical Trial Registration Number: Chinese Clinical Trial Registry with registration number ChiCTR2000034163.


Osteoarthritis, knee, overweight, pain, mobility, body mass index.


Centre for Sport and Exercise Sciences, University of Malaya, Kuala Lumpur, Sports Medicine Department, University of Malaya Medical Centre, Kuala Lumpur, Centre for Sport and Exercise Sciences, University of Malaya, Kuala Lumpur, Rehmatul-Lil-Alameen Postgraduate Institute of Cardiology, Punjab Employees Social Security Institution, Multan Chongi Multan Road Lahore, Department of Physical Medicine and Rehabilitation, Mayo Hospital Lahore

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