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Transport Properties of Cartilaginous Tissues

[ Vol. 5 , Issue. 1 ]

Author(s):

Alicia R. Jackson and Wei Yong Gu   Pages 40 - 50 ( 11 )

Abstract:


Cartilaginous tissues, such as articular cartilage and intervertebral disc, are avascular tissues, which rely on transport for cellular nutrition. Comprehensive knowledge of transport properties in such tissues is therefore necessary in the understanding of nutritional supply to cells. Furthermore, poor cellular nutrition in cartilaginous tissues is believed to be a primary source of tissue degeneration, which may result in osteoarthritis (OA) or disc degeneration. In this minireview, we present an overview of the current status of the study of transport properties and behavior in cartilaginous tissues. The mechanisms of transport in these tissues, as well as experimental approaches to measuring transport properties and results obtained are discussed. The current status of bioreactors used in cartilage tissue engineering is also presented.

, Transport, Properties, of, Cartilaginous, Tissues

Affiliation:

Department of Biomedical Engineering, College of Engineering, University of Miami, P.O. Box 248294, Coral Gables, FL 33124-0621, USA.



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